A placenta-specific receptor for the fusogenic, endogenous retrovirus-derived, human syncytin-2.

Abstract

Syncytin-2 is an envelope gene from the human endogenous retrovirus FRD (HERV-FRD) co-opted by an ancestral primate host, conserved in evolution over >40 Myr, specifically expressed in the placenta, and with a cell-cell fusogenic activity likely contributing to placenta morphogenesis. Here, using the GeneBridge4 human/Chinese hamster radiation hybrid panel… (More)
DOI: 10.1073/pnas.0807413105

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@article{Esnault2008APR, title={A placenta-specific receptor for the fusogenic, endogenous retrovirus-derived, human syncytin-2.}, author={C{\'e}cile Esnault and St{\'e}phane Priet and David Ribet and C{\'e}cile Vernochet and Thomas Bruls and Christian Lavialle and Jean Weissenbach and Thierry Heidmann}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2008}, volume={105 45}, pages={17532-7} }