A placebo-controlled trial of lamotrigine add-on therapy for partial seizures in children. Lamictal Pediatric Partial Seizure Study Group.

@article{Duchowny1999APT,
  title={A placebo-controlled trial of lamotrigine add-on therapy for partial seizures in children. Lamictal Pediatric Partial Seizure Study Group.},
  author={Michael S. Duchowny and J M Pellock and William D Graf and Catherine Billard and Jamie Gilman and Elena Casale and Gilda Womble and Marcus Risner and Penelope K Manasco},
  journal={Neurology},
  year={1999},
  volume={53 8},
  pages={1724-31}
}
OBJECTIVE To compare the safety and efficacy of add-on lamotrigine and placebo in the treatment of children and adolescents with partial seizures. BACKGROUND Add-on and monotherapy lamotrigine is safe and effective in adults with partial seizures, and reports of preliminary uncontrolled trials suggest similar benefits in children. METHODS We studied 201 children with diagnoses of partial seizures of any subtype currently receiving stable conventional regimens of antiepileptic therapy at 40… CONTINUE READING

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