A placebo controlled clinical trial of buprenorphine as a treatment for opioid dependence.

@article{Johnson1995APC,
  title={A placebo controlled clinical trial of buprenorphine as a treatment for opioid dependence.},
  author={Rolley E. Johnson and Thomas E Eissenberg and Maxine L. Stitzer and Eric C. Strain and Ira A. Liebson and George E. Bigelow},
  journal={Drug and alcohol dependence},
  year={1995},
  volume={40 1},
  pages={17-25}
}
Large-scale placebo controlled clinical trials assessing the efficacy of medications for the treatment of drug dependence have generally been limited to alcohol, cocaine and nicotine dependent populations. The purpose of the present study was to assess the early (1-2 week) clinical effectiveness of buprenorphine versus placebo in an opioid dependent population. The study used a parallel-group design with a behavioral choice component to compare buprenorphine (a mu-opioid partial agonist) to… CONTINUE READING

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