A placebo controlled, double-blind study of mecamylamine treatment for cocaine dependence in patients enrolled in an opiate replacement program.

@article{Reid2005APC,
  title={A placebo controlled, double-blind study of mecamylamine treatment for cocaine dependence in patients enrolled in an opiate replacement program.},
  author={Malcolm S. Reid and Burt Angrist and S. A. T. Baker and Siobhan O'leary and Jennifer Stone and Marion P. Schwartz and Deborah B Leiderman and Ann Montgomery and Ahmed Elkashef and Dorota Majewska and James L. Robinson and John Rotrosen},
  journal={Substance abuse},
  year={2005},
  volume={26 2},
  pages={5-14}
}
A placebo controlled, double-blind trial of mecamylamine treatment of cocaine dependence was performed in methadone or LAAM maintained subjects who met DSM-IV criteria for cocaine dependence. After an eight-week placebo run-in screening period, 35 subjects were randomly assigned to receive either mecamylamine (6 mg/day) or placebo transdermal patches for a 16-week treatment period. Outcome measures included quantitative urine benzoylecognine (BE) levels, self-report of cocaine use, cocaine… CONTINUE READING

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