A pilot trial comparing cerebral perfusion pressure-targeted therapy to intracranial pressure-targeted therapy in children with severe traumatic brain injury.

@article{Prabhakaran2004APT,
  title={A pilot trial comparing cerebral perfusion pressure-targeted therapy to intracranial pressure-targeted therapy in children with severe traumatic brain injury.},
  author={P. Joy Prabhakaran and A. Tirupathi Reddy and Walter Jerry Oakes and William D King and Margaret K Winkler and Timothy G Givens},
  journal={Journal of neurosurgery},
  year={2004},
  volume={100 5 Suppl Pediatrics},
  pages={454-9}
}
OBJECT The authors sought to compare cerebral perfusion pressure (CPP)- with intracranial pressure (ICP)-targeted therapy in children with severe traumatic brain injury (TBI). METHODS A randomized controlled trial was developed to assess CPP and ICP therapies in 17 children (range 15 months-15 years of age) with poststabilization Glasgow Coma Scale (GCS) scores of less than or equal to 8 who were admitted to a pediatric intensive care unit at a Level I trauma center. Goals in the ICP group… CONTINUE READING

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