A pilot trial assessing the efficacy of paroxetine hydrochloride (Paxil) in controlling hot flashes in breast cancer survivors.

@article{Stearns2000APT,
  title={A pilot trial assessing the efficacy of paroxetine hydrochloride (Paxil) in controlling hot flashes in breast cancer survivors.},
  author={Vered Stearns and Claudine Isaacs and Jon R Rowland and Jeffrey Crawford and Mathew Ellis and Rita Kramer and W E Lawrence and John J. Hanfelt and Daniel F. Hayes},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={2000},
  volume={11 1},
  pages={17-22}
}
BACKGROUND Many breast cancer survivors suffer debilitating hot flashes. Estrogen, the drug of choice in perimenopausal women, is generally not recommenced to breast cancer survivors. Nonhormonal treatments are mostly disappointing. Anecdotal reports in our institution suggested that the selective serotonin-reuptake inhibitor, paroxetine hydrochloride, might be efficacious in alleviating hot flashes. PATIENTS AND METHODS Thirty women with prior breast cancer who were suffering at least two… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 56 extracted citations

A review of paroxetine for the treatment of vasomotor symptoms.

Journal of pharmacy practice • 2015
View 4 Excerpts
Highly Influenced

Effect and safety of paroxetine for vasomotor symptoms: systematic review and meta-analysis.

BJOG : an international journal of obstetrics and gynaecology • 2016

References

Publications referenced by this paper.
Showing 1-10 of 20 references

Megestrol acetate for the prevention of hot flashes.

The New England journal of medicine • 1994
View 4 Excerpts
Highly Influenced

Clinical synthesis panel on HRT [ published erratum appears in

RT Chlebowski, A McTiernan
Lancet • 1999

Elements of informed consent for hormone replacement therapy in patients with diagnosed breast cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 1999
View 1 Excerpt

Health-related quality of life and tamoxifen in breast cancer prevention: a report from the National Surgical Adjuvant Breast and Bowel Project P-1 Study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 1999
View 2 Excerpts

Pilot evaluation of venlafaxine hydrochloride for the therapy of hot flashes in cancer survivors.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 1998
View 1 Excerpt

Prospective evaluation of vitamin E for hot flashes in breast cancer survivors.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 1998
View 3 Excerpts

Similar Papers

Loading similar papers…