A pilot study of vincristine, ifosfamide, and doxorubicin in the treatment of pediatric non-rhabdomyosarcoma soft tissue sarcomas.

@article{Walter1998APS,
  title={A pilot study of vincristine, ifosfamide, and doxorubicin in the treatment of pediatric non-rhabdomyosarcoma soft tissue sarcomas.},
  author={Andrew W. Walter and Patricia D. Shearer and Alberto S. Pappo and Cara Greenwald and B. Narasimha Rao and Laura C. Bowman and Wayne L. Furman and Amar Gajjar and Jesse J. Jenkins and Charles B. Pratt},
  journal={Medical and pediatric oncology},
  year={1998},
  volume={30 4},
  pages={210-6}
}
BACKGROUND Standard therapy for pediatric nonrhabdomyosarcoma soft tissue sarcomas (PNRSTS) consists of surgical resection with or without radiotherapy. The role of chemotherapy in the treatment of these tumors has not yet been defined. We investigated the efficacy and toxicity of an ifosfamide-based regimen in controlling disease in children with high-risk PNRSTS. PATIENTS AND METHODS Between January 1992 and June 1994 at St. Jude Children's Research Hospital, we treated 11 children and… CONTINUE READING