A pilot study of the predictive value of the probenecid test in application of 5-hydroxytryptophan as antidepressant

@article{Praag1972APS,
  title={A pilot study of the predictive value of the probenecid test in application of 5-hydroxytryptophan as antidepressant},
  author={Herman M. van Praag and Jakob Korf and Louise C. W. Dols and T. Schut},
  journal={Psychopharmacologia},
  year={1972},
  volume={25},
  pages={14-21}
}
In depressions, varying therapeutic effects have been obtained with 5-HT precursors. This is possibly due to the fact that the group of the depressions is pathogenetically heterogeneous; that, specifically, some types do and other types do not entail disturbances in the central 5-HT metabolism; and that only the former types are “precursor-sensitive”. This… CONTINUE READING