A pilot study of the effects of flumazenil on symptoms persisting after benzodiazepine withdrawal.

@article{Lader1992APS,
  title={A pilot study of the effects of flumazenil on symptoms persisting after benzodiazepine withdrawal.},
  author={Malcolm H. Lader and S. R. Morton},
  journal={Journal of psychopharmacology},
  year={1992},
  volume={6 3},
  pages={357-63}
}
The potential of the benzodiazepine antagonist flumazenil (Ro 15-1788) to lessen persisting benzodiazepine withdrawal symptoms was demonstrated in 11 patients who had been drug free for between 1 month and 5 years. Doses ranging from 0.2 to 2.0 mg divided into three intravenous injections over a few hours relieved long-standing symptoms to varying extents. These included clouded thinking, tiredness, muscular symptoms such as neck tension, cramps and shaking and the characteristic perceptual… CONTINUE READING
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Flumazenilprecipitated withdrawal symptoms in chronic users of therapeutic doses of diazepam

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