A pilot study of rapid whole-genome sequencing for the investigation of a Legionella outbreak

@inproceedings{Reuter2013APS,
  title={A pilot study of rapid whole-genome sequencing for the investigation of a Legionella outbreak},
  author={Sandra Reuter and Timothy G. Harrison and Claudio U K{\"o}ser and Matthew J. Ellington and Geoffrey Paul Smith and Julian Parkhill and Sharon J Peacock and Stephen D. Bentley and M Estee T{\"o}r{\"o}k},
  booktitle={BMJ open},
  year={2013}
}
OBJECTIVES Epidemiological investigations of Legionnaires' disease outbreaks rely on the rapid identification and typing of clinical and environmental Legionella isolates in order to identify and control the source of infection. Rapid bacterial whole-genome sequencing (WGS) is an emerging technology that has the potential to rapidly discriminate outbreak from non-outbreak isolates in a clinically relevant time frame. METHODS We performed a pilot study to determine the feasibility of using… CONTINUE READING
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