A pilot study of an oral phosphodiesterase inhibitor (apremilast) for atopic dermatitis in adults.

  title={A pilot study of an oral phosphodiesterase inhibitor (apremilast) for atopic dermatitis in adults.},
  author={Aman Samrao and Trista M Berry and Renato Goreshi and E L Simpson},
  journal={Archives of dermatology},
  volume={148 8},
OBJECTIVE To investigate the preliminary safety and efficacy of apremilast, an oral phosphodiesterase 4 inhibitor, for atopic dermatitis. DESIGN This investigator-initiated, open-label pilot study evaluated 2 doses of apremilast in patients with atopic dermatitis. Differential gene analysis was performed from peripheral whole blood using data before and after treatment. SETTING University-based dermatology clinical research unit. PATIENTS Sixteen adult patients with atopic dermatitis… CONTINUE READING
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Efficacy of ultraviolet A1 phototherapy on the expression of bcl-2 in atopic dermatitis and cutaneous T-cell lymphoma in vivo: a comparison study

  • F Breuckmann, G von Kobyletzki, A Avermaete, A Kreuter, P. Altmeyer
  • Photodermatol Photoimmunol Photomed
  • 2002
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