A pilot study comparing the purity, functionality and isoform composition of alpha-1-proteinase inhibitor (human) products.

@article{Cowden2005APS,
  title={A pilot study comparing the purity, functionality and isoform composition of alpha-1-proteinase inhibitor (human) products.},
  author={D I Cowden and Gary E. Fisher and Roger Weeks},
  journal={Current medical research and opinion},
  year={2005},
  volume={21 6},
  pages={877-83}
}
OBJECTIVE Alpha-1-proteinase deficiency predisposes affected individuals to early onset pulmonary emphysema, and is treated with an alpha-1-proteinase inhibitor (A1-PI) from pooled human plasma. The objective of this pilot study was to assess analytical parameters of the three A1-PI products (Aralast, Prolastin, Zemaira) that may impact on clinical efficacy, safety, and convenience. These included: purity of the preparation; nature of impurities; functionality; and isoform composition… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

Similar Papers

Loading similar papers…