A pilot genome wide association and gene expression array study of suicide with and without major depression.

@article{Galfalvy2013APG,
  title={A pilot genome wide association and gene expression array study of suicide with and without major depression.},
  author={Hanga C Galfalvy and Gil Zalsman and Yung-yu Huang and Lauren F. Murphy and Gorazd B. Rosoklija and Andrew J. Dwork and Fatima Haghighi and Victoria Arango and J. John Mann},
  journal={The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry},
  year={2013},
  volume={14 8},
  pages={574-82}
}
OBJECTIVES Suicide is partly heritable but the responsible genes have not been identified. We conducted a gene-centric, low coverage single nucleotide polymorphism (SNP) pilot genome-wide association study (GWAS) seeking new candidate regions in suicides with and without depression, combined with gene expression assay of brain tissue. METHODS Ninety-nine Caucasian subjects, including 68 who completed suicide and 31 who died suddenly from other causes, were genotyped postmortem using GeneChip… CONTINUE READING
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