A pig model of Huntington’s disease

@article{Stower2018APM,
  title={A pig model of Huntington’s disease},
  author={Hannah Stower},
  journal={Nature Medicine},
  year={2018},
  volume={24},
  pages={898-898}
}
Knock-in of the huntingtin gene in pigs recreates key features of Huntington’s disease. Huntington’s disease is a severe neurodegenerative monogenetic disease that results in age-dependent selective neuronal loss in affected individuals—a feature that cannot be mimicked in murine genetic models of the disease. Collaborators from the United States and China… CONTINUE READING