A physical-chemical model for cellular uptake of fatty acids: prediction of intracellular pool sizes.

@article{Cooper1987APM,
  title={A physical-chemical model for cellular uptake of fatty acids: prediction of intracellular pool sizes.},
  author={Ruth B Cooper and Noa Noy and David Zakim},
  journal={Biochemistry},
  year={1987},
  volume={26 18},
  pages={5890-6}
}
If the uptake of fatty acids by liver is a physical, not a biological, process, then the size and location of the intrahepatic pool of fatty acids can be predicted from uptake rates and thermodynamic data. The purpose of the experiments in this paper was to test the accuracy of this idea. Rat livers were perfused with palmitate bound to albumin, and the total amounts of palmitate removed from the perfusate were measured at 3-s intervals. The intrahepatic pools of palmitate calculated from these… CONTINUE READING

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