A photolabile ligand for light-activated release of caged copper.

  title={A photolabile ligand for light-activated release of caged copper.},
  author={Katie L. Ciesienski and Kathryn L Haas and Marina G. Dickens and Yohannes T. Tesema and Katherine J. Franz},
  journal={Journal of the American Chemical Society},
  volume={130 37},
A photosensitive caged copper complex has been prepared from a tetradentate ligand (H2cage) composed of two pyridyl-amide arms connected by a photoreactive nitrophenyl group. H2cage binds Cu2+ in aqueous solution with a stability constant (log beta) of 10.8, which corresponds to a KD of 16 pM at pH 7.4. The neutral Cu2+ complex, [Cu(OH2)(cage)], crystallizes as a distorted trigonal bipyramid coordinated by two amide and two pyridyl N atoms, with a water molecule bound in the trigonal plane… 

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