A phosphoinositide-linked dopamine D1 receptor mediates repetitive jaw movements in rats.

@article{Rosengarten1998APD,
  title={A phosphoinositide-linked dopamine D1 receptor mediates repetitive jaw movements in rats.},
  author={Helen Rosengarten and Arnold J. Friedhoff},
  journal={Biological psychiatry},
  year={1998},
  volume={44 11},
  pages={1178-84}
}
BACKGROUND We have demonstrated that rats injected with D1 agonists SKF 38393 or A68930 demonstrate repetitive jaw movements (RJM). These agonist-induced movements in rats are similar in their appearance to those induced in rats by long-term treatment with antipsychotic drugs. Over recent years D-1 receptors were discovered which showed linkage not only to c-AMP but also to PI hydrolysis. We examined the effect of EEDQ inactivation of D1 receptors on D-1 mediated PI hydrolysis and RJM… CONTINUE READING

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