A phosphoglucose isomerase mutant in Aspergillus nidulans is defective in hyphal polarity and conidiation.

@article{Upadhyay2006API,
  title={A phosphoglucose isomerase mutant in Aspergillus nidulans is defective in hyphal polarity and conidiation.},
  author={Srijana Upadhyay and Brian D. Shaw},
  journal={Fungal genetics and biology : FG & B},
  year={2006},
  volume={43 11},
  pages={739-51}
}
Upon germination Aspergillus nidulans swoM1 exhibits abnormal development by extending a primary germ tube that quickly reverts to isotropic growth and results in an enlarged, swollen apex with pronounced wall thickenings. Apical lysis occurs in 38% of the germlings. A point mutation in the AN6037.3 gene encoding the only phosphoglucose isomerase in A. nidulans is responsible for the defect. Loss of polarity is bypassed when glucose is replaced with alternate carbon sources but in all cases the… CONTINUE READING