A phenomenological examination of psilocybin use and its positive and persisting aftereffects

  title={A phenomenological examination of psilocybin use and its positive and persisting aftereffects},
  author={Joseph Zamaria},
This study is an examination of the positive and persisting psychological and behavioral aftereffects in eight individuals who reported consumption of psilocybin-containing mushrooms. Mushrooms containing psilocybin have been used for healing and spiritual purposes for thousands of years, and the therapeutic applications of psilocybin were scientifically examined beginning in the mid-20th century. Research from this era suggested that psilocybin was indicated as an effective adjunct to… Expand
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When administered under supportive conditions, psilocybin occasioned experiences similar to spontaneously occurring mystical experiences that, at 14-month follow-up, were considered by volunteers to be among the most personally meaningful and spiritually significant of their lives. Expand
Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance
When administered under supportive conditions, psilocybin occasioned experiences similar to spontaneously occurring mystical experiences, and the ability to occasion such experiences prospectively will allow rigorous scientific investigations of their causes and consequences. Expand
Mystical experiences occasioned by the hallucinogen psilocybin lead to increases in the personality domain of openness
Assessment of the effect of psilocybin on changes in the five broad domains of personality – Neuroticism, Extroversion, Openness, Agreeableness, and Conscientiousness found significant increases in Openness following a high-dose p silocybin session. Expand
Pilot study of psilocybin treatment for anxiety in patients with advanced-stage cancer.
This study established the feasibility and safety of administering moderate doses of psilocybin to patients with advanced-stage cancer and anxiety and revealed a positive trend toward improved mood and anxiety. Expand
Psilocybin occasioned mystical-type experiences: immediate and persisting dose-related effects
Under supportive conditions, 20 and 30 mg/70 kg psilocybin occasioned mystical-type experiences having persisting positive effects on attitudes, mood, and behavior. Expand
Safety, tolerability, and efficacy of psilocybin in 9 patients with obsessive-compulsive disorder.
In a controlled clinical environment, psilocybin was safely used in subjects with OCD and was associated with acute reductions in core OCD symptoms in several subjects. Expand
Prediction of Psilocybin Response in Healthy Volunteers
Having a high score in the personality trait of Absorption, being in an emotionally excitable and active state immediately before drug intake, and having experienced few psychological problems in past weeks were most strongly associated with pleasant and mystical-type experiences to psilocybin. Expand
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  • R. Strassman
  • Psychology, Medicine
  • The Journal of nervous and mental disease
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The basic pharmacology of the major synthetic psychedelic compounds (primarily lysergic acid diethylamide [LSD]-25) is described and reference is made to their potentially beneficial psychological effects. Expand
Dr. Leary's Concord Prison Experiment: a 34-year follow-up study.
  • R. Doblin
  • Psychology, Medicine
  • Journal of psychoactive drugs
  • 1998
The results of the follow-up study indicate that published claims of a treatment effect were erroneous and supports the emphasis in the original reports on the necessity of embedding psilocybin-assisted psychotherapy with inmates within a comprehensive treatment plan that includes post-release, nondrug group support programs. Expand