A phase II trial of weekly paclitaxel and high-dose 5-fluorouracil plus leucovorin in patients with chemotherapy-pretreated metastatic breast cancer.

@article{Lin2007API,
  title={A phase II trial of weekly paclitaxel and high-dose 5-fluorouracil plus leucovorin in patients with chemotherapy-pretreated metastatic breast cancer.},
  author={C R Lin and Ann-lii Cheng and C. -P. Hsu and Yen-shen Lu and Chiun Yu Hsu and Kun-Huei Yeh and Chen-Yao Wu and Chiun-Sheng Huang and C J Yang},
  journal={Anticancer research},
  year={2007},
  volume={27 1B},
  pages={641-5}
}
BACKGROUND Weekly paclitaxel and infusional high-dose 5-fluorouracil/leucovorin (HDFL) are both effective regimens for metastatic breast cancer (MBC) patients. PATIENTS AND METHODS A study was designed using weekly paclitaxel 90 mg/m(2) 1-hour infusion followed by 2,000 mg/m(2) 5-fluorouracil plus 300 mg/m(2) leucovorin 24-hour infusion on days 1, 8 and… CONTINUE READING