A phase II trial of paclitaxel and weekly 24 h infusion of 5-fluorouracil/folinic acid in patients with advanced gastric cancer.

@article{Bokemeyer1997API,
  title={A phase II trial of paclitaxel and weekly 24 h infusion of 5-fluorouracil/folinic acid in patients with advanced gastric cancer.},
  author={C Carsten Bokemeyer and Cliff Lampe and Michael R. Clemens and Joerg Thomas Hartmann and D. Quietzsch and Lutz Forkmann and Christian K. Kollmannsberger and Lothar Kanz},
  journal={Anti-cancer drugs},
  year={1997},
  volume={8 4},
  pages={396-9}
}
A phase II trial was performed to evaluate the efficacy and toxicity of the combination of paclitaxel and 5-fluorouracil (5-FU)/folinic acid in patients with advanced gastric carcinoma. Twenty-two patients (six female and 16 male) with advanced or metastatic disease were enrolled. None of them had received prior chemotherapy. Paclitaxel was administrated as a 3 h infusion of 175 mg/m2 at days 1 and 22, 5-FU 2000 mg/m2 i.v. over 24 h and folinic acid 500 mg/m2 i.v. 2 h prior to 5-FU weekly from… CONTINUE READING

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