A phase II study of preoperative oxaliplatin, capecitabine, and external beam radiotherapy in patients with locally advanced rectal adenocarcinoma. : Abstract #3552

@inproceedings{Duck2004API,
  title={A phase II study of preoperative oxaliplatin, capecitabine, and external beam radiotherapy in patients with locally advanced rectal adenocarcinoma. : Abstract #3552},
  author={Lionel Duck and Christine Sempoux and Brigitte Honhon and Bernard de Coster and J C Coche and Joseph Kerger and J. Canon and Yves Humblet and Pascale Cornette and Dorte Lisbet Nielsen},
  year={2004}
}
3552 Background: Local recurrence after surgery is a cause of treatment failure in pts with locally advanced rectal cancer (LARC). Preoperative RT decreases local recurrence but not distant spread. Oxaliplatin (OX) and capecitabine (CAP) are both highly active cancer drugs for advanced colorectal cancer and have radiosensitizing properties. Therefore, adding CAP and OX to preoperative RT should improve its efficacy in terms of local control and prevention of metastases. Methods: This study was… CONTINUE READING

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