A phase II study of bromocriptine in patients with androgen-independent prostate cancer.

@article{Horti1998API,
  title={A phase II study of bromocriptine in patients with androgen-independent prostate cancer.},
  author={J{\'o}zsef Horti and William D. Figg and B H Weinberger and David A. Kohler and Oliver A Sartor},
  journal={Oncology reports},
  year={1998},
  volume={5 4},
  pages={
          893-6
        }
}
Prolactin is an important physiological regulator of prostate development and growth in preclinical models. In prostate cancer there is strong evidence that prolactin exerts a trophic effect independent of testosterone. In addition, patients with prostate cancer that have an elevated prolactin level correlated with a poorer prognosis. Based on these data, we evaluated the clinical effect of prolactin suppression using bromocriptine in patients with androgen-independent prostate cancer. We… CONTINUE READING
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