A phase II study of amrubicin combined with carboplatin for elderly patients with small-cell lung cancer: North Japan Lung Cancer Study Group Trial 0405.

@article{Inoue2010API,
  title={A phase II study of amrubicin combined with carboplatin for elderly patients with small-cell lung cancer: North Japan Lung Cancer Study Group Trial 0405.},
  author={Akira Inoue and Osamu Ishimoto and Shinichi Fukumoto and Kazuhiro Usui and Toshiro Suzuki and Hiroshi Yokouchi and Makoto Maemondo and Mariko Kanbe and Shigeaki Ogura and Toshiyuki Harada and Satoshi Oizumi and Masao Harada and Shunichi Sugawara and Takayuki Fukuhara and Toshihiro Nukiwa},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={2010},
  volume={21 4},
  pages={800-3}
}
BACKGROUND Amrubicin, a new anthracycline agent, has shown high activity for small-cell lung cancer (SCLC) in previous studies. However, a combination regimen with amrubicin and platinum has been investigated little. On the basis of previous phase I study, we conducted this study to evaluate the efficacy and the safety of amrubicin and carboplatin for elderly patients with SCLC. METHODS Chemotherapy-naive elderly patients with SCLC received amrubicin (35 mg/m(2), days 1-3) and carboplatin… CONTINUE READING

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