A phase II pilot study to evaluate use of intravenous lidocaine for opioid-refractory pain in cancer patients.

@article{Sharma2009API,
  title={A phase II pilot study to evaluate use of intravenous lidocaine for opioid-refractory pain in cancer patients.},
  author={Shekhar Sharma and M. R. Rajagopal and Gayatri Palat and Charu Singh and Altaf Gauhar Haji and Dimpel Jain},
  journal={Journal of pain and symptom management},
  year={2009},
  volume={37 1},
  pages={85-93}
}
Opioid-refractory pain is distressing because it is notoriously difficult to treat. Relief from adjuvant therapies often occurs after a lag time. Retrospective evidence points to a role for intravenous (IV) lidocaine in this setting for pain relief. This study was planned as a randomized, double-blind, placebo-controlled, crossover study in which eligible patients received both lidocaine and placebo infusions separated by two weeks. Primary endpoints were magnitude and duration of pain relief… CONTINUE READING

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Pharmacological Management of Cancer-Related Pain.

Cancer control : journal of the Moffitt Cancer Center • 2015

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