A phase I trial of tocoferol monoglucoside in patients undergoing hemi-body radiation.

  title={A phase I trial of tocoferol monoglucoside in patients undergoing hemi-body radiation.},
  author={N. Huilgol and C. Nair and P. Merhotra and V. Kagiya},
  journal={Journal of cancer research and therapeutics},
  volume={1 1},
  • N. Huilgol, C. Nair, +1 author V. Kagiya
  • Published 2005
  • Medicine
  • Journal of cancer research and therapeutics
  • PURPOSE To evaluate Tocoferol monoglucoside (TMG), a water soluble vit. E. in a phase I trial, as a radiation protector in those undergoing hemi-body radiation for disseminated disease. MATERIALS AND METHODS Patients scheduled to receive modified hemi-body radiation were accrued for the study. Patients not only had disseminated skeletal disease but, were heavily pretreated Seven patients were accrued for the study. Patients received 1 and 2 gms of TMG. 30-40 minutes before hemibody radiation… CONTINUE READING
    6 Citations
    First Chemical Evaluation and Toxicity of Casinga-cheirosa to Balb-c Male Mice
    • 15
    • PDF
    Prevention of cisplatin-induced nephrotoxicity by glucosides of ascorbic acid and alpha-tocopherol.
    • 75


    Radiotherapeutic studies with amifostine (Ethyol).
    • 41
    The oxygen dependence of protection by aminothiols: implications for normal tissues and solid tumors.
    • E. Travis
    • Medicine
    • International journal of radiation oncology, biology, physics
    • 1984
    • 49
    Radioprotection of mouse skin by WR-2721: the critical influence of oxygen tension.
    • 53
    E as a radioprotector
    • Indian J Exp Biol
    • 2003
    Water soluble Vit E (TMG) as a radio protector
    • Indian J Exp Biol
    • 2003
    Inhibition of gamma-radiation-induced DNA damage in plasmid pBR322 DNA by TMG, a derivative of Vitamin E
    • J Radiat Res
    • 2002
    Radioprotection membrane damage by TMG. International conference on Natural Antioxidants and Free Radicals in Human Health and Radiation Biology, Mumbai
    • Abstract Book;
    • 2001
    Vit.E and genome stability, a tocoferol
    • Mutation Research
    • 2001