A phase I study of chemoembolization with cisplatin and lipiodol for primary and metastatic liver cancer.

@article{Feun1994API,
  title={A phase I study of chemoembolization with cisplatin and lipiodol for primary and metastatic liver cancer.},
  author={Lynn G. Feun and K Rajender Reddy and Jose M. Yrizarry and Niramol Savaraj and J. Jo{\~a}o Paulo Guerra and Roger K. Purser and Stuart Waldman and Jo{\'e} U. Levi and Frank Moffatt and Lauren Morrell},
  journal={American journal of clinical oncology},
  year={1994},
  volume={17 5},
  pages={
          405-10
        }
}
Twenty patients with either unresectable primary hepatocellular carcinoma or hepatic metastases were entered into a chemoembolization program with cisplatin and lipiodol; 19 patients were evaluable for response. Doses of cisplatin ranged from 40 to 100 mg/m2. Toxicity was tolerable and reversible and included abdominal pain, transient elevation in serum creatinine, serum bilirubin, and serum transaminases. Less common side effects include fever, ascites or pleural effusion, and hiccups. Two of… CONTINUE READING
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