A phase I and pharmacokinetic study of liposomal vinorelbine in patients with advanced solid tumor

@article{Yang2010API,
  title={A phase I and pharmacokinetic study of liposomal vinorelbine in patients with advanced solid tumor},
  author={Shih-Hung Yang and Chia-Chi Lin and Z Lin and Y Tseng and R G Hong},
  journal={Investigational New Drugs},
  year={2010},
  volume={30},
  pages={282-289}
}
Purpose This phase I study was performed to determine the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) of an untargeted liposomal formulation of vinorelbine (NanoVNB®) and to characterize its plasma pharmacokinetics in patients with advanced solid tumors which were refractory to conventional treatment or without an effective treatment… CONTINUE READING