A pharmacological study of oesophageal muscularis mucosae from the cat, dog and American opossum (Didelphis virginiana).

@article{Christensen1984APS,
  title={A pharmacological study of oesophageal muscularis mucosae from the cat, dog and American opossum (Didelphis virginiana).},
  author={James Christensen and William H. Percy},
  journal={British journal of pharmacology},
  year={1984},
  volume={83 2},
  pages={
          329-36
        }
}
Strips of muscularis mucosae from the oesophagi of cat, dog and opossum have been studied to determine their responses to drugs to electrical field stimulation. All tissues were contracted by acetylcholine, histamine and, with the exception of strips of muscularis mucosae from the opossum proximal oesophagus, noradrenaline. The effects of acetylcholine and histamine were competitively antagonized by atropine (50 nM) and mepyramine (50 nM) and were abolished by atropine (1 microM) and mepyramine… CONTINUE READING
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