A pharmacological comparison of 3-methoxy-4,5-methylenedioxyamphetamine and LSD in the dog.

@article{Nozaki1978APC,
  title={A pharmacological comparison of 3-methoxy-4,5-methylenedioxyamphetamine and LSD in the dog.},
  author={M. Nozaki and D. Bruce Vaupel and L D Bright and William R. Martin},
  journal={Drug and alcohol dependence},
  year={1978},
  volume={3 3},
  pages={
          153-63
        }
}
3-Methoxy-4,5-methylenedioxyamphetamine (MMDA), which has been reported to have hallucinogenic actions in man, was compared to LSD in single dose, antagonist interaction, cross-tolerance and appetite suppression studie in the dog. In single doses, MMDA partially resembled LSD: both facilitated the flexor reflex and produced tachypnea, hyperthermia, and analgesia; however, MMDA had greater activity than LSD in producing mydriasis. Only LSD consistently elicited the stepping reflex and produced… 
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