A pharmacologic analysis of chronotropic and inotropic responses to direct electrical stimulation of the isolated, blood-perfused canine atrium.

Abstract

Electrical stimulation on the posterior portion in the caval margin of the right atrium caused a biphasic chronotropic and inotropic response, i.e., a negative response followed by a positive response, in the isolated blood-perfused canine atrial preparation. The threshold of pulse duration for inducing negative responses was approximately 0.05 msec at 2 v… (More)

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Cite this paper

@article{Furukawa1980APA, title={A pharmacologic analysis of chronotropic and inotropic responses to direct electrical stimulation of the isolated, blood-perfused canine atrium.}, author={Yoichi Furukawa and M. Kobayashi and Sayuri Chiba}, journal={Japanese heart journal}, year={1980}, volume={21 6}, pages={873-82} }