A pharmacokinetic study of clofoctol in human plasma and lung tissue by using a microbiological assay.

@article{Danesi1988APS,
  title={A pharmacokinetic study of clofoctol in human plasma and lung tissue by using a microbiological assay.},
  author={Romano Danesi and Matteo Gasperini and Sonia Senesi and Giulia Freer and Carlo Alberto Angeletti and Mario del Tacca},
  journal={Drugs under experimental and clinical research},
  year={1988},
  volume={14 1},
  pages={39-43}
}
A microbiological assay was undertaken to measure the amounts of clofoctol in human plasma and pulmonary tissue, and to investigate its pharmacokinetics. Clofoctol was extracted from samples using ethanol and the concentration of drug in the extracts was determined by the broth macrodilution method using as reference microorganisms S. aureus ATCC 29213 and B. cereus NCIB 8122, whose MIC values were 0.537 and 1.074 micrograms/ml respectively. This procedure allows the almost complete recovery of… CONTINUE READING

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