A pharmaco-EEG study on antipsychotic drugs in healthy volunteers

  title={A pharmaco-EEG study on antipsychotic drugs in healthy volunteers},
  author={Masafumi Yoshimura and Thomas Koenig and Satoshi Irisawa and Toshiaki Isotani and Keizo Yamada and Mitsuru Kikuchi and Gaku Okugawa and Takami Yagyu and Toshihiko Kinoshita and Werner Strik and Thomas Dierks},
Both psychotropic drugs and mental disorders have typical signatures in quantitative electroencephalography (EEG). Previous studies found that some psychotropic drugs had EEG effects opposite to the EEG effects of the mental disorders treated with these drugs (key–lock principle). We performed a placebo-controlled pharmaco-EEG study on two conventional antipsychotics (chlorpromazine and haloperidol) and four atypical antipsychotics (olanzapine, perospirone, quetiapine, and risperidone) in… CONTINUE READING


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Perospirone (Sumitomo Pharmaceuticals)

  • T de Paulis
  • Curr Opin Investig Drugs
  • 2002
Highly Influential
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