A personalized and optimal approach for dosing contrast material at coronary computed tomography angiography


A method for constructing a personalized contrast medium protocol at contrast enhanced, Coronary CT Angiography (CCTA) is presented. A one compartment pharmacokinetic model is parameterized and identified with a minimal data set from a test-bolus injection. A direct-search optimization is performed to construct a protocol that achieves target enhancement in… (More)
DOI: 10.1109/IEMBS.2009.5334533


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