A permutation-based method to identify loss-of-heterozygosity using paired genotype microarray data

Abstract

Background SNP genotyping microarrays may be used to detect regions of loss-of-heterozygosity (LOH). Genotype array data are collected for tumor tissue and germline tissue samples from each subject. For each subject, an initial call of LOH or non-LOH is generated for each marker via straightforward comparison of the genotype call across each tissue sample… (More)
DOI: 10.1186/1471-2105-9-S7-P12

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@inproceedings{Pounds2008APM, title={A permutation-based method to identify loss-of-heterozygosity using paired genotype microarray data}, author={Stan Pounds and Cheng Cheng and Wenjian Yang and Arzu Onar and Christine Hartford and Susana C. Raimondi and Mary V Relling}, booktitle={BMC Bioinformatics}, year={2008} }