A peripheral blood gene expression score is associated with plaque volume and phenotype by intravascular ultrasound with radiofrequency backscatter analysis: results from the ATLANTA study.

@article{Joshi2013APB,
  title={A peripheral blood gene expression score is associated with plaque volume and phenotype by intravascular ultrasound with radiofrequency backscatter analysis: results from the ATLANTA study.},
  author={Parag Joshi and Sarah Rinehart and Gustavo Vazquez and Zhen Qian and Abhinav Sharma and Hunt Anderson and Laura Murrieta and Nancy Flockhart and Dimitrios Karmpaliotis and Anna M Kalynych and Bela F. Asztalos and Michael R. Elashoff and John S Blanchard and Steven Rosenberg and Charles Brown and Szilard Voros},
  journal={Cardiovascular diagnosis and therapy},
  year={2013},
  volume={3 1},
  pages={5-14}
}
BACKGROUND A composite, peripheral gene expression score based on quantitative RNA-measurements has been validated for detecting stenosis against invasive coronary X-ray angiography. IVUS/VH has been validated for quantitative measurements of coronary plaque volume and composition and has been shown to be predictive of outcomes and treatment effects. The correlation between peripheral gene expression and coronary plaque composition by intravascular ultrasound with radiofrequency backscatter… CONTINUE READING

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