A peptidomic approach for monitoring and characterising peptide cyanotoxins produced in Italian lakes by matrix-assisted laser desorption/ionisation and quadrupole time-of-flight mass spectrometry.

@article{Ferranti2011APA,
  title={A peptidomic approach for monitoring and characterising peptide cyanotoxins produced in Italian lakes by matrix-assisted laser desorption/ionisation and quadrupole time-of-flight mass spectrometry.},
  author={Pasquale Ferranti and Antonella Nasi and Milena Bruno and Adriana Basile and Luigi Serpe and Pasquale Gallo},
  journal={Rapid communications in mass spectrometry : RCM},
  year={2011},
  volume={25 9},
  pages={1173-83}
}
In recent years, the occurrence of cyanobacterial blooms in eutrophic freshwaters has been described all over the world, including most European countries. Blooms of cyanobacteria may produce mixtures of toxic secondary metabolites, called cyanotoxins. Among these, the most studied are microcystins, a group of cyclic heptapeptides, because of their potent hepatotoxicity and activity as tumour promoters. Other peptide cyanotoxins have been described whose structure and toxicity have not been… CONTINUE READING

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