A peak in gh-receptor expression is associated with growth activation in Atlantic salmon vertebrae, while upregulation of igf-I receptor expression is related to increased bone density.

@article{Wargelius2005API,
  title={A peak in gh-receptor expression is associated with growth activation in Atlantic salmon vertebrae, while upregulation of igf-I receptor expression is related to increased bone density.},
  author={Anna Wargelius and Per-Gunnar Fjelldal and Susana Benedet and Tom Troels Hansen and Bj{\"o}rn Thrandur Bj{\"o}rnsson and Ulla Nordgarden},
  journal={General and comparative endocrinology},
  year={2005},
  volume={142 1-2},
  pages={163-8}
}
Growth hormone (GH) and insulin-like growth factor-I (IGF-I) play major roles in the endocrine regulation of fish growth, but their interdependency and mode of action has not been well elucidated. The GH-IGF-I system is essential for normal vertebral growth in mouse, but this has not been studied in fish. To study the interplay between GH, IGF-I, and their receptors, postsmolt Atlantic salmon were studied during spring growth (January-June 2003). From January to June, fish were sampled… CONTINUE READING

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