A pattern-based nearest neighbor search approach for promoter prediction using DNA structural profiles

@article{Gan2009APN,
  title={A pattern-based nearest neighbor search approach for promoter prediction using DNA structural profiles},
  author={Yanglan Gan and Jihong Guan and Shuigeng Zhou},
  journal={Bioinformatics},
  year={2009},
  volume={25 16},
  pages={2006-12}
}
MOTIVATION Identification of core promoters is a key clue in understanding gene regulations. However, due to the diverse nature of promoter sequences, the accuracy of existing prediction approaches for non-CpG island (simply CGI)-related promoters is not as high as that for CGI-related promoters. This consequently leads to a low genome-wide promoter prediction accuracy. RESULTS In this article, we first systematically analyze the similarities and differences between the two types of promoters… CONTINUE READING

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