A pathway of costimulation that prevents anergy in CD28- T cells: B7- independent costimulation of CD1-restricted T cells

Abstract

A class of molecules that is expressed on antigen presenting cells, exemplified by CD80 (B7), has been found to provide a necessary costimulatory signal for T cell activation and proliferation. CD28 and CTLA4 are the B7 counterreceptors and are expressed on the majority of human CD4+ T cells and many CD8+ T cells. The signal these molecules mediate is… (More)

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Cite this paper

@article{Behar1995APO, title={A pathway of costimulation that prevents anergy in CD28- T cells: B7- independent costimulation of CD1-restricted T cells}, author={Samuel M Behar and Steve A Porcelli and Evan M Beckman and Michael Brenner}, journal={The Journal of Experimental Medicine}, year={1995}, volume={182}, pages={2007 - 2018} }