A pathway linking reward circuitry, impulsive sensation-seeking and risky decision-making in young adults: identifying neural markers for new interventions

@inproceedings{Chase2017APL,
  title={A pathway linking reward circuitry, impulsive sensation-seeking and risky decision-making in young adults: identifying neural markers for new interventions},
  author={Henry W. Chase and Jay C. Fournier and Michele A. Bertocci and Tsafrir Greenberg and Haris A Aslam and Richelle S Stiffler and Jeanette C Lockovich and Simona Graur and Genna M Bebko and Erika E. Forbes and Mary L. Phillips},
  booktitle={Translational Psychiatry},
  year={2017}
}
High trait impulsive sensation seeking (ISS) is common in 18–25-year olds, and is associated with risky decision-making and deleterious outcomes. We examined relationships among: activity in reward regions previously associated with ISS during an ISS-relevant context, uncertain reward expectancy (RE), using fMRI; ISS impulsivity and sensation-seeking subcomponents; and risky decision-making in 100, transdiagnostically recruited 18–25-year olds. ISS, anhedonia, anxiety, depression and mania were… CONTINUE READING