A pathology atlas of the human cancer transcriptome

@article{Uhln2017APA,
  title={A pathology atlas of the human cancer transcriptome},
  author={M. Uhl{\'e}n and Cheng Zhang and Sunjae Lee and E. Sj{\"o}stedt and L. Fagerberg and G. Bidkhori and R. Benfeitas and M. Arif and Z. Liu and F. Edfors and Kemal Sanli and Kalle von Feilitzen and P. Oksvold and E. Lundberg and S. Hober and P. Nilsson and J. Mattsson and J. Schwenk and H. Brunnstr{\"o}m and B. Glimelius and T. Sj{\"o}blom and P. Edqvist and D. Djureinovic and P. Micke and C. Lindskog and A. Mardinoglu and F. Pont{\'e}n},
  journal={Science},
  year={2017},
  volume={357}
}
Cancer is one of the leading causes of death, and there is great interest in understanding the underlying molecular mechanisms involved in the pathogenesis and progression of individual tumors. [...] Key Method We used systems-level approaches to analyze the genome-wide transcriptome of the protein-coding genes of 17 major cancer types with respect to clinical outcome. A general pattern emerged: Shorter patient survival was associated with up-regulation of genes involved in cell growth and with down-regulation…Expand
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