A pathologic assessment of tumor residue and stromal changes after intraarterial chemotherapy for head and neck carcinomas. A study on serial sections of the whole surgical specimen.

@article{Sulfaro1989APA,
  title={A pathologic assessment of tumor residue and stromal changes after intraarterial chemotherapy for head and neck carcinomas. A study on serial sections of the whole surgical specimen.},
  author={Sandro C Sulfaro and Sergio Frustaci and Rachele Volpe and Luigi Barzan and Roberto Comoretto and Silvio Monfardini and Antonino Carbone},
  journal={Cancer},
  year={1989},
  volume={64 5},
  pages={994-1001}
}
Thirty-one patients with advanced, biopsy-proven squamous cell carcinoma (SCC) of the head and neck were treated with intraarterial chemotherapy (IAC) and subsequent radical surgery. Cisplatin at 25 mg/d (4 hours of infusion) and bleomycin at 15 mg/d (20 hours of infusion) were administered for 10 consecutive days. Radical surgery was performed after clinical evaluation 2 weeks later. Clinical tumor regression (total disappearance or shrinkage of the tumor mass by more than 50%) was recorded in… CONTINUE READING

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