A paternally imprinted X chromosome retards the development of the early mouse embryo.


It has previously been shown that XO mouse fetuses with a paternally derived X chromosome (Xp) are developmentally retarded and consequently smaller than their XX sibs, and that XX fetuses are retarded when compared with their XY sibs. The genetic basis for these early XO-XX and XX-XY differences has not been determined. Here we show that 10.5 day post… (More)

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