A parametric approach to voxel-based meta-analysis

  title={A parametric approach to voxel-based meta-analysis},
  author={Sergi G. Costafreda and Anthony S. David and Michael J. Brammer},
  volume={46 1},
A key aim of meta-analysis in functional neuroimaging is to quantify the consistency of regional cerebral responses across studies. We derive here a parametric approach to voxel-based meta-analysis, based on spatial statistics. In this method, the value of each voxel in the meta-analysis summary map reflects the proportion of studies reporting an activation within a specified local neighborhood. We threshold this map by testing whether voxel scores could have been expected had the activation… CONTINUE READING