A parametric analysis of punishment frequency as a determinant of the response to chlordiazepoxide in the Vogel conflict test in rats.


The Vogel conflict test has been widely used as a methodology for detecting anxiolytic-like effects of drugs with a broad spectrum of pharmacological activities. Despite widespread acceptance of the Vogel assay as a preclinical predictor of efficacy for anxiolytic-like compounds, detailed parametrics have not been reported on the optimization of this assay… (More)


  • Presentations referencing similar topics