A panic experimental model: validation of a complex operant behavioral method in undernourished rats, with desipramine to provide a template effect profile.

Abstract

INTRODUCTION Clinical studies have shown that some antidepressants may be more efficient than benzodiazepines to alleviate anxiety associated with panic disorders; however, operant conflict procedures in rats developed so far seem not particularly able to model human anxiety sensitive to antidepressant treatments. Previous panic models with learned… (More)

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@article{Vigliecca2007APE, title={A panic experimental model: validation of a complex operant behavioral method in undernourished rats, with desipramine to provide a template effect profile.}, author={Nora Silvana Vigliecca and Silvia Cristina Molina and Marisa Carola Pe{\~n}alva}, journal={Journal of pharmacological and toxicological methods}, year={2007}, volume={55 1}, pages={49-57} }