A panel of ancestry informative markers for estimating individual biogeographical ancestry and admixture from four continents: utility and applications

@article{Halder2008APO,
  title={A panel of ancestry informative markers for estimating individual biogeographical ancestry and admixture from four continents: utility and applications},
  author={I. Halder and M. Shriver and M. Thomas and J. R. Fern{\'a}ndez and Tony N. Frudakis},
  journal={Human Mutation},
  year={2008},
  volume={29}
}
  • I. Halder, M. Shriver, +2 authors Tony N. Frudakis
  • Published 2008
  • Biology, Medicine
  • Human Mutation
  • Autosomal ancestry informative markers (AIMs) are useful for inferring individual biogeographical ancestry (I‐BGA) and admixture. Ancestry estimates obtained from Y and mtDNA are useful for reconstructing population expansions and migrations in our recent past but individual genomic admixture estimates are useful to test for association of admixture with phenotypes, as covariate in association studies to control for stratification and, in forensics, to estimate certain overt phenotypes from… CONTINUE READING
    249 Citations

    Topics from this paper

    Paper Mentions

    Interventional Clinical Trial
    Determine differences in serum vitamin D metabolism by genetic ancestry.  
    ConditionsVitamin D Deficiency
    InterventionDietary Supplement
    Developing a novel panel of genome-wide ancestry informative markers for bio-geographical ancestry estimates.
    • 27
    • Highly Influenced

    References

    SHOWING 1-10 OF 44 REFERENCES
    A genomewide single-nucleotide-polymorphism panel with high ancestry information for African American admixture mapping.
    • 171
    Skin pigmentation, biogeographical ancestry and admixture mapping
    • 469
    • PDF
    A high-density admixture map for disease gene discovery in african americans.
    • 442
    • PDF
    Estimating African American admixture proportions by use of population-specific alleles.
    • 742
    • PDF
    Ethnic-difference markers for use in mapping by admixture linkage disequilibrium.
    • 131
    • PDF
    Measuring and using admixture to study the genetics of complex diseases
    • 87
    Admixture in the Hispanics of the San Luis Valley, Colorado, and its implications for complex trait gene mapping
    • 155
    • Highly Influential
    • PDF