A pandemic clonal lineage of the wheat blast fungus

  title={A pandemic clonal lineage of the wheat blast fungus},
  author={Sergio M. Latorre and Vincent M. Were and Andrew J. Foster and Thorsten Langner and Angus Malmgren and Adeline Harant and Soichiro Asuke and Sarai Reyes-Avila and Dipali Rani Gupta and Cassandra Jensen and Weibin Ma and Nur Uddin Mahmud and Md. Sh{\aa}bab Mehebub and Rabson M. Mulenga and Abu Naim Md. Muzahid and Sanjoy Kumar Paul and S. M. Fajle Rabby and Abdullah Al Mahbub Raha and Lauren S. Ryder and Ram Krishna Shrestha and Suwilanji Sichilima and Darren M. Soanes and Pawan Kumar Singh and Alison R. Bentley and Diane G. O. Saunders and Yukio Tosa and Daniel Croll and Kurt H Lamour and Tofazzal Islam and Batiseba Tembo and Joe Win and Nicholas J. Talbot and Hern{\'a}n A. Burbano and Sophien Kamoun},
Wheat, the most important food crop, is threatened by a blast disease pandemic. Here, we show that a clonal lineage of the wheat blast fungus recently spread to Asia and Africa following two independent introductions from South America. Through a combination of genome analyses and laboratory experiments, we show that the decade-old blast pandemic lineage can be controlled by the Rmg8 disease resistance gene and is sensitive to strobilurin fungicides. However, we also highlight the potential of… 
Rapid mini-chromosome divergence among fungal isolates causing wheat blast outbreaks in Bangladesh and Zambia
Global wheat production is seriously threatened by the filamentous fungal pathogen, Magnaporthe oryzae, causing wheat blast disease. The pathogen was first identified in South America and recently
The transcriptional landscape of plant infection by the rice blast fungus Magnaporthe oryzae reveals distinct families of temporally co-regulated and structurally conserved effectors
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Evolution of the wheat blast fungus through functional losses in a host specificity determinant
Study on avirulence and resistance gene distributions, together with historical data on wheat cultivation in Brazil, suggest that wheat blast emerged due to widespread deployment of rwt3 wheat (susceptible to Lolium isolates), followed by the loss of function of PWT3, which implies that the rWT3 wheat served as a springboard for the host jump to common wheat.
Emergence of wheat blast in Bangladesh was caused by a South American lineage of Magnaporthe oryzae
The findings suggest that genomic surveillance can be rapidly applied to monitor plant disease outbreaks and provide valuable information regarding the identity and origin of the infectious agent.
Gene Flow between Divergent Cereal- and Grass-Specific Lineages of the Rice Blast Fungus Magnaporthe oryzae
Greater understanding of the ecoevolutionary factors that underlie the diversification of M. oryzae is provided and the practicality of genomic data for epidemiological surveillance in this important multihost pathogen is highlighted.
Resistance to QoI Fungicides Is Widespread in Brazilian Populations of the Wheat Blast Pathogen Magnaporthe oryzae.
The widespread distribution of QoI resistance in M. oryzae populations sampled from wheat fields and poaceous hosts across central and southern Brazil and the evolution of the cytochrome b (cyt b) gene indicate an urgent need to reexamine the use of strobilurins to manage fungal wheat diseases in Brazil.
Population structure and pathotype diversity of the wheat blast pathogen Magnaporthe oryzae 25 years after its emergence in Brazil.
It is proposed that populations of the wheat blast pathogen exhibit a mixed reproductive system in which sexual reproduction is followed by the local dispersal of clones.
Effector gene reshuffling involves dispensable mini-chromosomes in the wheat blast fungus
It is reported that recent wheat pathogens can contain one or two highly-variable conditionally-dispensable mini-chromosomes, each with an amalgamation of effector sequences that are duplicated or absent from pathogen core chromosome ends.
Genome comparison of two Magnaporthe oryzae field isolates reveals genome variations and potential virulence effectors
This work used a next generation sequencing approach to analyze the genomes of two field isolates FJ81278 and HN19311 and identified extensive polymorphisms including unique genes, SNPs and indels, structural variations, copy number variations, and loci under strong positive selection.
Suppression of wheat blast resistance by an effector of Pyricularia oryzae is counteracted by a host specificity resistance gene in wheat.
It is shown that Rmg8, a promising wheat gene for resistance breeding, is suppressed by PWT4, an effector gene of P. oryzae, and in turn, that the suppression is counteracted by Rwt4, a wheat gene recognizing P WT4.
The Lolium Pathotype of Magnaporthe oryzae Recovered from a Single Blasted Wheat Plant in the United States.
It is shown that M. oryzae strains capable of infecting wheat have existed in the United States for at least 16 years and that the environmental conditions in Princeton during the spring of 2011 were unusually conducive to the early production of blast inoculum.
Rmg8 and Rmg7, wheat genes for resistance to the wheat blast fungus, recognize the same avirulence gene AVR-Rmg8.
AVR-Rmg8, an avirulence gene corresponding to Rmg7, was isolated from a wheat blast isolate through a map-based strategy and encoded a small protein containing a putative signal peptide, suggesting that these two resistance genes are equivalent to a single gene from the viewpoint of resistance breeding.