A pH-responsive cyclodextrin-based hybrid nanosystem as a nonviral vector for gene delivery.

Abstract

The absence of safe, efficient, cost-effective, and easily scalable delivery platforms is one of the most significant hurdles and critical issues that limit the bench to bedside translation of oligonucleotides-based therapeutics. Acid-labile materials are of special interest in developing nonviral vectors due to their capability of intracellularly… (More)
DOI: 10.1016/j.biomaterials.2013.02.035

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Cite this paper

@article{Chen2013APC, title={A pH-responsive cyclodextrin-based hybrid nanosystem as a nonviral vector for gene delivery.}, author={Huaping Chen and Xueping Liu and Yin Dou and Binfeng He and Li Liu and Zhenghua Wei and Jin Li and Changzheng Wang and Chengde Mao and Jianxiang Zhang and Guansong Wang}, journal={Biomaterials}, year={2013}, volume={34 16}, pages={4159-72} }